RVFamSq

Rare Variant-Family-Based Score Test for Quantitative Traits

Description

The RVFamSq package provides an efficient approach to examine the association between the region-based rare variants and the quantitative traits in family-based data. The RVFamsSq can be broadly applied to diverse pedigrees with members missing sequence data. In addition, qualitative and quantitative covariates, e.g., age, sex, and body mass index, can be flexibly included. The speed of the package is significantly optimized to analyze large-scale data sets.

Quick Start

  1. Follow the setup instructions below.

  2. See the Quick Start Example for an introduction to RVFamSq.

Setup

To install the package,

library("devtools")
install_github('statgenetics/RVFamSq')

Developer notes

To build documentation for the package,

setwd("/path/to/package/root")
devtools::document()

Please do not manually edit any .Rd files under man folder!

To build the documentation website (make sure you are connected to Internet while running these commands):

setwd("/path/to/package/root")
devtools::document()
pkgdown::build_site()

To install locally from source code via devtools,

setwd("/path/to/package/root")
devtools::document()
devtools::install()